Therapeutic targeting of ALS pathways: Refocusing an incomplete picture.

There was no influence on survival but a slightly significant positive impact on vital capacity. 80 The potential for any future evaluation of trophic factors, including those listed above, may have to wait for more sophisticated methods of delivery to the CNS via infusion or viral vector delivery of these compounds that allow for sustained production of these factors while mitigating side effects.

also in 1,756 other papers