Small Molecules Temporarily Induce Neuronal Features in Adult Canine Dermal Fibroblasts.

Int J Mol Sci · 2023 · PMC10648228 · PMID 37958789

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showed a trendno p-value reported

Additional Treatment in 2D Culture, 3D Culture, and In Vivo Conditions of Spinal Cord Injury Diminishes Neuronal Protein Expression in Small Molecule-Treated Adult Canine Dermal Fibroblasts Genetic analysis revealed that upregulated neuronal genes such as MAP2 and TUBB3 showed a trend to be diminishing the expression level, implying that neuronal induction is temporary.

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an increasing trendno p-value reported

Although they were not statistically significant, the proportions of ACDFs exhibiting neuronal morphology showed an increasing trend from Day 1 to Day 12.

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