Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading.

Arthritis Res Ther · 2005 · PMC1064896 · PMID 15642136

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did not reach statistical significanceno p-value reported

Higher expression in OA samples was also evident at 6 weeks, but owing to a large standard deviation the difference did not reach statistical significance.

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