Downregulation of Heat Shock Protein 72 Contributes to Fibrostenosis in Crohn's Disease.

Gut Liver · 2023 · PMC10651382 · PMID 36814356

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showed a trendno p-value reported

Although the gene expression levels of all markers showed a trend consistent with that of the proteomic analysis, statistical analysis showed that only HSPA1A (HSP72) and HSPA5 (GRP78) among the genes of the five candidate proteins were significantly reduced in fibrostenotic samples compared to inflamed tissues; the other genes had no significant differences compared to normal control or inflamed CD groups ( Fig. 3 ). 2.

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