Protectin DX as a therapeutic strategy against frailty in mice.

Geroscience · 2023 · PMC10651819 · PMID 37059838

Europe PMC DOI

hedged sentence

0.0760

closest p · 1.5× alpha

0.0760

boldest claim

The sentences

showed a trendp = 0.076so close (0.05 < p ≤ 0.1)

PDX treatment showed a trend to attenuate the increase in circulating MCP-1 in female animals ( p = 0.076.) Aging produces numerous transcriptional changes in the liver, a subset of which are partially reversed by PDX treatment We sequenced RNA extracted from the liver of 15 female mice, five from each experimental group, in order to assess the transcriptional consequences of aging and PDX treatment.

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