M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice.

mBio · 2023 · PMC10653841 · PMID 37768050

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M2a Mφ markers, Arg1, and Chil3 mRNA levels were significantly reduced in TLR4-SNP colons at Days 9 and 11, while Mrc1 mRNA showed a trend toward reduced M2a gene expression in TLR4-SNP colon sections compared to WT mice, particularly at Day 9 ( Fig. 4A ).

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