The HPV8 E6 protein targets the Hippo and Wnt signaling pathways as part of its arsenal to restrain keratinocyte differentiation.

mBio · 2023 · PMC10653872 · PMID 37676018

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did not reach statistical significanceno p-value reported

HPV8 E6 also enhanced the expression of AMOTL2 mRNA at high cell density, although this increase did not reach statistical significance ( Fig. 3C ).

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