In the TCGA-LUAD training, TCGA-LUAD testing, and TCGA-LUAD sets, the high-risk group showed a trend of higher sensitivity to standard chemotherapy drugs (Cisplatin, Docetaxel, Etoposide, Gemcitabine, Paclitaxel, and Vinorelbine) (Fig. 3 B and Additional file 4: Figure S3 B, S3 C).
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Characterization of genomic instability-related genes predicts survival and therapeutic response in lung adenocarcinoma.
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