Intestinal Atp8b1 dysfunction causes hepatic choline deficiency and steatohepatitis.

Nat Commun · 2023 · PMC10663612 · PMID 37990006

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Metabolomic analysis showed a trend toward decreased choline metabolites in the plasma and liver of Atp8b1 IEC-KO mice (line #12) compared to the littermate Atp8b1 flox/flox mice (Fig. 4c–e ).

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