Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson's study.

NPJ Parkinsons Dis · 2023 · PMC10667262 · PMID 37996455

Europe PMC DOI

hedged sentence

0.2900

closest p · 5.8× alpha

0.2900

boldest claim

The sentences

showed a trendp = 0.29not close (p > 0.1)

Severe PD GBA1 variant carriers showed a trend towards younger AAO compared to mild and risk (severe: 58.6 ± 13.1 vs mild: 65.4 ± 17 vs risk: 62.5 ± 9.3 years; p = 0.29) (Table 3 ), with a significant risk to develop early onset PD (OR = 4.02; p = 0.0098).

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