Discriminating between Homogeneous (AC-1) and Dense Fine Speckled (AC-2) Antinuclear Antibody Patterns: Re-Evaluation of Immunofluorescence Imaging

Biomedicines · 2023 · PMC10669234

Europe PMC

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an increasing trendno p-value reported

An increasing trend over time of prevalence of anti-DFS70 autoantibodies was observed among the US population [ 27 ].

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near statistical significanceno p-value reported

In the subgroup analysis of patient samples only (excluding subjects for health examination), the OR of detection of anti-nucleosome/histone/dsDNA using AC-1 in the original data was 1.36 (95% confidence interval, CI 0.33–5.61, p -value = 0.67); furthermore, the OR of detection of anti-nucleosome/histone/dsDNA using AC-1 in the re-evaluated data increased to 5.43 (95% CI 1.00–29.61, p -value = 0.05), which was near statistical significance.

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