Importantly, HLA-DRB1*14:54 , which has never been reported in patients with PAP, was only detected in the aPAP group rather than the sPAP group ( p = 0.030), and HLA-DRB1*14:54 carriers showed a trend towards higher response rates to inhaled GM-CSF therapy.
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HLA-DRB1*14:54 Is Associated with Pulmonary Alveolar Proteinosis: A Retrospective Real-World Audit
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