Depletion of Labile Iron Induces Replication Stress and Enhances Responses to Chemoradiation in Non-Small-Cell Lung Cancer.

Furthering the observed cell specificity, these effects were not observed in the A549 cells that were Ft-H overexpressed and, while treatment with DFO was able to promote SSBs, it did not reach statistical significance ( Figure 3 D).

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