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The Metabolic Fingerprint of Doxorubicin-Induced Cardiotoxicity in Male CD-1 Mice Fades Away with Time While Autophagy Increases.

Pharmaceuticals (Basel) · 2023 · PMC10675798 · PMID 38004479

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0.0800
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The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)
Doxorubicin Treatment Decreased the Cardiac Content of the Metabolic Regulator AMP-Activated Protein Kinase (AMPK), and Increased the Cardiac Content of Electron Transfer Flavoprotein-Ubiquinone Oxidoreductase (ETF-QO) One Week after Exposure The content of glucose transporter GLUT4 (GLUT4), which allows the import of glucose into cardiac cells [ 20 ], showed a trend to be decreased in the DOX1 group compared to CTRL1 ( p = 0.08, Figure 3 ), probably indicating a reduced uptake of glucose.

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