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1725. Differences in serotype 3 antibody response and antibody functionality compared to serotype 19A following 13-valent pneumococcal conjugate immunization in children

Open Forum Infect Dis · 2023 · PMC10679009

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a negative trendno p-value reported
In contrast, PCV13-immunized children showed a negative trend of antibody levels with age.

also in 2,480 other papers

a positive trendno p-value reported
Serotype 3 natural- immunized children showed a positive trend of increase in antibody level as children got older.

also in 6,774 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.