We observed an increase in CD7 linked to a mature Treg phenotype [ 66 ] and a significant trend towards increased CST7 (log 2 FC 0.37, confidence interval: 0.59 to 0.16) associated with TCR signaling [ 67 ].
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GITR and TIGIT immunotherapy provokes divergent multicellular responses in the tumor microenvironment of gastrointestinal cancers.
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