A linear-by-linear association test revealed that an increasing trend in the GAIS score was significantly associated with the FMR+AFL side compared with the AFL side, both for those provided by the participants ( p =0.021) and investigators ( p <0.001).
Conversely, on the AFL side, sebum secretion slightly increased at week 20 (93.3±40.1 μg/cm 2 ) compared to that at baseline (81.9±14.4 μg/cm 2 ); however, this difference failed to reach statistical significance ( Fig. 5E ).
Significant differences between the two groups were noted by RM-ANOVA ( p =0.048), yet they failed to reach significance for specific time points in the post-hoc analysis ( Fig. 2 ).