Resistance exercise protects mice from protein-induced fat accretion.

Despite the increased liver weight of the HP groups, they did not have increased lipid accumulation; instead, there was a nonsignificant trend toward both larger and a greater number of liver lipid droplets in the LP-fed groups, with no effect of WP ( Figure 2A–C ).

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In agreement with our prior home-cage observations and the well-known satiating effect of dietary protein, we observed that HP-fed mice tended to consume less food than LP-fed mice, although this did not reach statistical significance ( Figure 3—figure supplement 1A ).

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