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Irisin reduces orthodontic tooth movement in rats by promoting the osteogenic potential in the periodontal ligament.

Eur J Orthod · 2023 · PMC10687601 · PMID 37209709

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Although a trend of reduced OTM was recorded between the 0.1 μg irisin group and control group at days 6, 9, 12, and 14, this failed to reach statistical significance ( Figure 4A ).

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