Urinary markers of the alternative and lectin complement pathway are increased in IgA vasculitis nephritis.

Masp-1 Similar findings were reported for MASP-1 with a 2.8-fold increase in urinary concentrations in the patients with IgAVN (116.9 ± 116.7 ng/mmol) when compared to the cohort of HCs (41.4 ± 56.1 ng/mmol; P = 0.006); but did not reach statistical significance between IgAVN and IgAVwoN (73.0 ± 88.4 ng/mmol; P = 0.240) and between IgAVwoN and HCs (Fig. 3a ).

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