The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation.

Nat Neurosci · 2023 · PMC10689245 · PMID 37957317

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showed a trendno p-value reported

The E3 neurons also showed a trend of reduced Tau-488 uptake (~20%) compared to E4 neurons, although not reaching significance.

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