Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression.

However, compared with the cells with stably knocked out MLYCD expression, the content of malonyl-CoA, the rate of de novo FA synthesis, and the activity of CPT1a were scarcely significant in RCC cells with stable knockdown of HIF2α expression and knockout MLYCD expression ( Fig. 6B ).

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