Post-radiation xerostomia therapy with allogeneic mesenchymal stromal stem cells in patients with head and neck cancer: study protocol for phase I clinical trial.

However, in a pilot study, the same group has already used MSC prepared in this manner in six patients who received a single injection of 10×10 6 MSC into a single mandibular salivary gland and found that the therapy was well tolerated and showed a trend toward improvement in salivary volume and quality of life. 42 To our knowledge, there has been no research using allogeneic MSCs from umbilical cord tissue.

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