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Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration.

Transl Vis Sci Technol · 2023 · PMC10691387 · PMID 38019498

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In later research, the same group found the critical duration to be longer in patients with AMD compared to healthy controls, but this difference failed to reach statistical significance. 63 On the basis of this research, it was hypothesized that temporal resolution produces sufficient stress on rod and cone photoreceptors to detect a measurable reduction of sensitivity in AMD, whereas the temporal summation of light photons does not. 63 Notably, temporal summation was not measured under conditions of conventional perimetry; instead, red stimuli of 0.25° diameter were used.

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