Consistent with the previous reports [ 18 , 19 , 21 ], treatment with ASP7657 significantly increased the population of CD8 + T cells and showed a trend towards increasing CD4 + and total T cells in tumors.
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Blockade of EP4 by ASP7657 Modulates Myeloid Cell Differentiation In Vivo and Enhances the Antitumor Effect of Radiotherapy.
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