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Plasma Tryptophan-Kynurenine Pathway Metabolites and Risk for Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes.

Diabetes Care · 2023 · PMC10698226 · PMID 37796480

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A high KTR was associated with an increased risk for ESKD in the univariable model (unadjusted HR 1.40 [1.05, 1.86]), but the strength of the association did not reach statistical significance after adjustment for clinical risk factors (adjusted HR 1.29 [0.89, 1.87]).

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