Environmental enrichment reverses stress-induced changes in the brain-gut axis to ameliorate chronic visceral and somatic hypersensitivity.

Bonferroni's post-hoc tests showed an association between stress and increased GR expression in the hippocampus (sham = 100 ± 15.2 vs WAS = 135.2 ± 36.1; p = 0.039) and EE showed a trend of reducing GR levels back to normal however, this difference was not significant (EE + WAS = 111.8 ± 27.9; p = 0.11) ( Fig. 6 F). 5.

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