CoCl<sub>2</sub> -triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299.

FEBS Open Bio · 2023 · PMC10699113 · PMID 37803520

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nearly significantno p-value reported

The T 1/2 for SIRT4(K78R) was approximately 1.6‐fold increased as compared to wild‐type SIRT4, whereas its difference to SIRT4(K299R) was nearly significant.

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