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Dinaciclib synergizes with BH3 mimetics targeting BCL-2 and BCL-X<sub>L</sub> in multiple myeloma cell lines partially dependent on MCL-1 and in plasma cells from patients.

Mol Oncol · 2023 · PMC10701777 · PMID 37704591

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Nevertheless, FISH− samples tend to be more sensitive to S63845 than altered ones, but this tendency did not reach statistical significance due to the wide range of responses.

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