The Role of Phosphatidylethanolamine N-Methyltransferase (<i>PEMT</i>) and Its Waist-Hip-Ratio-Associated Locus rs4646404 in Obesity-Related Metabolic Traits and Liver Disease.

Int J Mol Sci · 2023 · PMC10706059 · PMID 38069170

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nominally significantno p-value reported

Although previous GWAS reported a nominally significant sexual dimorphism for rs4646404 [ 7 ], we found no sex–SNP interaction effects in the linear regression analyses in the present study.

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a decreasing trendno p-value reported

Although there was no statistically significant association between rs4646404 and sc PEMT mRNA expression, a decreasing trend with reduced PEMT mRNA expression in sc AT in carriers of the A allele was found ( Figure 6 B).

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