delbrueckii significantly downregulated the level of IL-4 ( P = 0.0405) in sera, although the serum level of IFN-ɣ ( P = 0.8335) increased, however, this increase failed to reach statistical significance (Fig. 5 D).
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A new generation of mesenchymal stromal/stem cells differentially trained by immunoregulatory probiotics in a lupus microenvironment.
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Despite clear signs of inflammation in the P–C group by the end of the experiment, engrafted D-MSCs or R-MSCs severely affected the infiltration of cells, resulting in a highly significant proteinuria reduction.