Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer.

However, in comparisons of A3A (red) and A3B (blue) APOBEC3 TCW mutation frequencies in ssDNA loop regions of hairpins and equivalent data sets from aggregate controls (blue boxes: the catalytic mutant of each protein and eGFP), the A3A data set approaches statistical significance (P = 0.0655) and the A3B data are significantly different (P = 0.0367) by Welch’s t-test.

also in 34 other papers

The A3A versus control comparison likely failed to reach statistical significance due to the small number of clones with WGS (n = 6) and the large variance in numbers of TCW mutations in hairpin loop regions in the different clones (range = 1–16 TCW mutations).

also in 1,120 other papers