Barely Significant
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Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial Fibrillation: Systematic Review and Meta-Analysis.

JACC Asia · 2023 · PMC10715893 · PMID 38095004

Europe PMCDOI
1
hedged sentence
0.1400
closest p · 2.8× alpha
0.1400
boldest claim

The sentences

did not reach statistical significanceP = 0.140not close (p > 0.1)
Similar significance was seen in the subgroups of PSM studies (HR: 0.81; 95% CI: 0.73-0.89; P < 0.001; I 2 = 44%) ( Figure 3 ) and patients aged 65-75 years old (HR: 0.80; 95% CI: 0.70-0.91; P < 0.001; I 2 = 0%) ( Supplemental Figure 1 ) but not for the subgroup of patients aged ≥75 years old, which had a trend favoring DOAC that did not reach statistical significance (HR: 0.94; 95% CI: 0.87-1.02; P = 0.140; I 2 = 23%) ( Supplemental Figure 2 ).

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