Therapeutic effect of adipose-derived mesenchymal stem cells in a porcine model of abdominal sepsis.

Stem Cell Res Ther · 2023 · PMC10717819 · PMID 38087374

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highly significantno p-value reported

A highly significant increase in IL-1Ra, IL-1b, IL-6, IL-8, TNF-α, and IL-10 was observed 24 h after induction of abdominal infection in all animals (at this time point, all groups had similar values).

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did not reach statistical significanceno p-value reported

At day 7, levels of IL-1Ra, IL-2, and IL-6 were elevated in the control group, but only IL-2 was elevated in the ADSC-treated groups, and we observed a significant decrease in IFNγ between the two treatment groups: The high-dose group showed more increased or decreased values, although the differences did not reach statistical significance.

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