The NF-kBp65 showed a trend toward upregulation in the vehicle-treated LPS group compared to the naïve and EV-treated LPS groups, but the differences were statistically insignificant (Fig. 7 O).
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Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus.
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