In this respect, although STARD7 has not been shown to directly regulate CL remodeling, we were able to detect significant remodeling of one CL species 5 days after shifting Dmef2-Gal4; tub-Gal80 ts /UAS-dSTARD7 RNAi-1 flies to 27°C, and many other CL species showed a trend of remodeling, although the changes were not deemed statistically significant ( Table S1 ).
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Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity.
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