Barely Significant
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Value of digital rectal examination in patients with suspected prostate cancer: a prospective cohort analysis study.

Transl Androl Urol · 2023 · PMC10719765 · PMID 38106690

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an unfavorable trendno p-value reported
The incidence of PCa in China is steadily increasing, and over the past 30 years, the disease burden caused by PCa has further escalated, indicating an unfavorable trend ( 2 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.