Antihypertensives associated adverse events: a review of mechanisms and pharmacogenomic biomarkers available evidence in multi-ethnic populations.

Front Pharmacol · 2023 · PMC10722273 · PMID 38108069

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modest significanceno p-value reported

Although no associations with genome-wide significance were detected, two associations with modest significance were reported. rs500766 (g.6508628C>T) in protein kinase C theta ( PRKCQ ) was found to decrease the risk of ACEIs-AE if the patient carries at least one copy of the alternative allele.

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