An update on mechanisms of pruritus and their potential treatment in primary cutaneous T-cell lymphoma.

Clin Exp Med · 2023 · PMC10725374 · PMID 37555911

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showed a trendno p-value reported

Numerous clinical trials have confirmed that topical application of capsaicin – a TRPV1 agonist – is effective in reducing chronic pruritus of unknown origin [ 274 , 275 ], and PAC-14028, a TRPV1 antagonist, showed a trend towards improvement of pruritus in AD patients in a phase 2b clinical trial [ 276 , 277 ] (Table 1 ).

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