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Peripheral blood lymphocytes predict clinical outcomes in hormone receptor-positive HER2-negative advanced breast cancer patients treated with CDK4/6 inhibitors.

Ther Adv Med Oncol · 2023 · PMC10734364 · PMID 38130467

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showed a trendno p-value reported
Indeed, while the precocious reduction of neutrophil counts during CDK4/6i therapy showed a trend toward an association with better patient PFS, CDK4/6i-induced reduction of monocyte and platelet counts was even associated with a trend toward worse PFS ( Supplemental Figure 5–7 ).

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