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Comprehensive Comparison of AAV Purification Methods: Iodixanol Gradient Centrifugation vs. Immuno-Affinity Chromatography.

Adv Cell Gene Ther · 2023 · PMC10735247 · PMID 38130431

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However, in vivo testing demonstrated opposite results, as POR AAV5 trended to transduce the livers of WT BALB/c mice better than IOD AAV5, although this difference did not reach statistical significance ( Figure 5(b) ).

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