MiR-217 Regulates SIRT1 Expression and Promotes Inflammatory and Apoptotic Responses in Osteoarthritis.

Pro-caspase 3 protein levels were also increased, compared to the miR-217 inhibitor group, but did not reach statistical significance ( Figure 4 B).

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The prevalence of radiographic OA shows an increasing trend with each decade of life, fluctuating from 33% among adults over 60 years to almost 45% over 80 years [ 3 ].

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