Barely Significant
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Transcriptomic profiling of the response to excess iodide in Keap1 hypomorphic mice reveals new gene-environment interactions in thyroid homeostasis.

Redox Biol · 2024 · PMC10746517 · PMID 38048653

Europe PMCDOI
1
hedged sentence
0.0660
closest p · 1.3× alpha
0.0660
boldest claim

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near-significantp = 0.066so close (0.05 < p ≤ 0.1)
We therefore compared the pituitary mRNA expression levels of β-TSH (measured by RT-PCR as a highly sensitive marker of thyroid function [ 20 ] by two-way ANOVA; the results showed a significant effect of the genotype (p = 0.011), a near-significant effect of iodide treatment (p = 0.066), and no interaction effect between genotype and treatment (p = 0.98), indicating that the Keap1 genotype does not modify the effect of iodide overload on thyroid function ( Fig. 3 C).

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