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Contrasting effects of whole-body and hepatocyte-specific deletion of the RNA polymerase III repressor <i>Maf1</i> in the mouse.

Front Mol Biosci · 2023 · PMC10746880 · PMID 38143800

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showed a trendp -value < 0.1so close (0.05 < p ≤ 0.1)
However, twenty additional metabolites showed a trend towards differential abundance at a relaxed stringency ( p -value < 0.1), with most showing fold changes smaller but in the same direction as in Maf1 −/− mice, pointing to effects on the same pathways.

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