IFITM1 and IFITM3 Proteins Inhibit the Infectivity of Progeny HIV-1 without Disrupting Envelope Glycoprotein Clusters.

Inhibition of gp160 processing by IFITM3 was observed across four independent panels of viruses, while reduction in Env cleavage in IFITM1 pseudoviruses did not reach statistical significance ( Figure 1 E).

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