HER2 positivity predicts BCG unresponsiveness and adaptive immune cell exhaustion in EORTC risk-stratified cohort of bladder cancer.

Front Immunol · 2023 · PMC10748406 · PMID 38143745

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hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

marginally significantp = 0.08so close (0.05 < p ≤ 0.1)

The results indicated a marginally significant difference in HER2+ between the low-to-intermediate and high-to-very-high-risk groups ( p = 0.08), with a significant difference observed within subcategories ( p < 0.05).

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did not reach statistical significanceno p-value reported

Although patients in the HER2+ group demonstrated a higher EORTC-R score ( p = 0.79) and a tendency towards more frequent recurrences ( p = 0.08) than those in the HER2+ group, these differences did not reach statistical significance. 3.3 Predictive factors for RFS Table 2 shows the results of the univariate analysis for RFS in the total cohort of 160 patients and a subset of 67 who received BCG induction therapy.

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