Druggable genomic landscapes of high-grade gliomas.

Front Med (Lausanne) · 2023 · PMC10749203 · PMID 38143440

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Targeted therapies that demonstrated clinical efficacy in phase 2 trials compared to drugs that lacked clinical efficacy, showed a trend toward lower IC 50 in GBM-specific cell lines (mean rank 8.80 vs. 11.64 μM, Kruskal Wallis p -value: 0.26; Supplementary Table S6 ).

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