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Gastric inhibitory polypeptide receptor antagonism suppresses intramuscular adipose tissue accumulation and ameliorates sarcopenia.

J Cachexia Sarcopenia Muscle · 2023 · PMC10751449 · PMID 37897141

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The mRNA expression levels of Wisp1 , Bmp3b and follistatin in the TA muscles tended to be increased in GIP receptor antagonist‐treated Gipr +/+ mice relative to untreated Gipr +/+ mice, although their differences did not reach statistical significance ( Figure 5 D ).

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