Barely Significant
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Genomic inbreeding measures applied to a population of mice divergently selected for birth weight environmental variance.

Front Genet · 2023 · PMC10752941 · PMID 38155710

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a negative trendno p-value reported
due to a negative individual increase in inbreeding produced by a negative trend of inbreeding coefficients in the first two generations, which was probably produced by the abrupt change in mating design.

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a positive trendno p-value reported
Expected homozygosity presented a positive trend when data from all individuals was used and when selected lines were analysed separately.

also in 6,779 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.