Examining the Relationship and Prognostic Significance of Cell-Free DNA Levels and the PSMA-Positive Tumor Volume in Men with Prostate Cancer: A Retrospective-Prospective [⁶⁸Ga]Ga-PSMA-11 PET/CT Study.

Although we did not observe a significant correlation between hemoglobin and cfDNA levels, a negative trend was tangible.

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However, as there was a slight trend ( Fig. 5B ) toward lower survival probabilities in the high-cfDNA group, we hypothesize that our study might be underpowered to detect survival differences based on cfDNA concentrations, as only 19 patients had passed until the date of censoring (May 2023).

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